When I first read this category, I thought to myself, "This has to be a Kamina scene." And sure enough, that opinion hasn't changed. But which one? There are so many to choose from. So I picked the most epic one, the one that was the most meaningful to the series. You know which one it is.
KAMINA'S GIGA DRILL BREAKER & DEATH (TENGEN TOPPA GURREN LAGANN)
Kamina is the manliest character to ever exist. He is the very definition of what it is to be a man. He inspires those around him while not slacking off. He aims for impossible goals and sets out to achieve them. He doesn't even last the whole series, but Kamina is by far the most memorable character in TTGL.
Unfortunately he dies. In episode 8, Kamina is skewered through the heart by a large robot immediately after knocking the sense back into Simon. But you know what? Screw that. Despite being, for all intents and purposes, a dead man, Kamina comes back to save the day.
Simon is flustered after the death and Kamina can sense that. He wakes up, says some very inspirational things, and does one final combination and attack with Simon, the iconic Giga Drill Breaker. He immediately dies afterwards, but not without saying goodbye to his friends.
It's not often you can say you avenged your own death, but Kamina is so manly that he can do so. Truly one to remember.